OCTOBER 4, 2018

New Study Tries to Address PEG 3350 Safety Concerns

Some reassuring news about the safety of long-term use of polyethylene glycol (PEG) 3350 for constipation—maybe.

Researchers in Ohio have found that using the medication daily for two weeks does not increase blood glycol beyond levels regarded as safe by regulators (J Pediatr 2018;195:148-153.e1). However, others say the effort to put patient anxieties to rest may have raised even more safety concerns about the laxative, which has been linked to neuropsychiatric side effects.

“The