PBC

A Stepwise Approach to Patients With Abnormal Liver Enzymes

Abnormal liver tests are a common occurrence in the United States.

JUNE 5, 2025

Expert Picks From The Liver Meeting 2024

In this second part of a two-part series, Ashwani Singal, MD, MS, discusses abstracts on treatment of severe ...

MAY 22, 2025

New PBC Drugs Show Sustained Efficacy in Extension Studies

Elafibranor and seladelpar, both recently approved by the FDA for treatment of PBC, showed prolonged efficacy and ...

MAY 20, 2025

Elafibranor Significantly Improves Prognosis For Patients With PBC, Study Finds

Elafibranor is predicted to increase transplant-free survival and reduce mortality over 15 years in patients with ...

FEBRUARY 13, 2025

Accelerated FDA Approval Ushers In New Era in Primary Biliary Cholangitis Treatment

The FDA’s recent accelerated approval of seladelpar for the treatment of PBC is a critical advancement for ...

JANUARY 13, 2025

FDA Issues Serious Liver Injury Warning for Obeticholic Acid

The FDA has issued a warning of serious liver injury for patients taking obeticholic acid for primary biliary ...

DECEMBER 16, 2024

Obeticholic Acid Proves Its Mettle As Second-Line Therapy for PBC

Patients with primary biliary cholangitis treated with obeticholic acid as second-line therapy within the POISE ...

NOVEMBER 29, 2022

Promising New Second-Line Therapy for Primary Biliary Cholangitis Emerges, More Data to Come

Seladelpar could eventually become the standard second-line treatment for primary biliary cholangitis, according to ...

MARCH 9, 2021

Pipeline Rich for Bile Acid Drugs

Arlington, Va.—Hepatologists treating patients with cholangiopathies have had few options. But that might be ...

OCTOBER 3, 2018

Fibrates Gaining Favor for PBC

Arlington, Va.—With only two treatment options for primary biliary cholangitis, some hepatologists have cast ...

AUGUST 21, 2018

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