Decoding IBD: 5 Practice-Changing Lessons

Managing inflammatory bowel disease involves precise diagnosis, vigilant monitoring and strategic treatment selection.

AUGUST 25, 2025

The Regueiro Report

Upadacitinib in Perianal Fistulizing CD; IBS Symptoms in IBD

The first study in The Regueiro Report this month assesses the efficacy and safety of upadacitinib for people with perianal fistulizing Crohn’s disease.

AUGUST 14, 2025

Alcohol Use Associated With UC Flares

Many patients with IBD have long attested that alcohol has harmful effects on their condition, and data from a meta-analysis presented at DDW 2025 support this notion.

AUGUST 7, 2025

Upadacitinib Appears Safe, Effective In Older Adults With UC

Upadacitinib is safe for adults 50 years of age and older with moderate to severe UC, according to retrospective study data presented at DDW 2025.

JULY 29, 2025

Cognitive Behavioral Therapy Decreased Pain, Improved Sleep in Crohn’s Patients

Cognitive behavioral therapy decreased pain and improved some measures of sleep in a study of patients with Crohn’s disease suffering from insomnia.

JULY 22, 2025

The Regueiro Report

The Global Evolution of IBD; Withdrawing Anti-TNF Therapy for IBD in Remission

This month's Regueiro Report looks at one of the most important papers about the epidemiology of IBD to appear for several years, perhaps even decades, and I suspect it will be highly cited in years to come.

JULY 17, 2025

The Regueiro Report

White-Light Endoscopy for Cancer Detection, Capsule Endoscopy to Guide CD Treatment

This month, I focus on different endoscopic techniques that gastroenterologists might use, one for CRC detection in patients with IBD and another to guide treat-to-target decision-making when assessing disease activity in patients with Crohn’s disease.

JUNE 30, 2025

A #MondayNightIBD Conversation

Approach to a Patient With IBD-Associated Peripheral Spondyloarthropathies

Extraintestinal manifestations are common in patients with IBD. They usually appear during the course of IBD, but in 25% of cases, they precede or are concurrent with IBD diagnosis.

JUNE 20, 2025

Diet Modification in Youths With IBD May Exacerbate ARFID, Study Finds

Treatment of IBD often includes dietary modification, which commonly is perceived as a low-risk intervention compared with medication or surgery.

JUNE 13, 2025

SubQ Guselkumab Found to Hit All Targets by 12 Weeks

Subcutaneous administration of guselkumab resulted in achievement of all study end points in people with moderate to severely active UC in the phase 3 ASTRO trial.

JUNE 9, 2025

Predicting and Mitigating Maternal IBD Transmission to Infants

Maternal IBD is associated with an increased risk for IBD in children, but it may be possible to modify this risk.

JUNE 4, 2025

The Regueiro Report

Risankizumab After Advanced Therapy for UC; GLP-1s for IBD

The first study in The Regueiro Report this month is a post hoc analysis of two successful phase 3 trials, INSPIRE and COMMAND.

MAY 28, 2025