In the prospective, multicenter, randomized TOPAZ trial, colon capsule endoscopy (CCE) performed better than computed tomography colonography (CTC) in detecting polyps in an average-risk colon cancer screening population.
CTC is a tier 2 test for colorectal cancer screening and CCE is a tier 3 test, according to the U.S. Multi-Society Task Force on Colorectal Cancer (Am J Gastroenterol 2017;112[7]:1016-1030). However, the new findings support boosting CCE to a tier 2 test, according to the