San Diego—In patients who have undergone a polypectomy, the antidiabetic drug metformin provides protection against the development of new adenomas and polyps, according to a double-blind, placebo-controlled, Phase III trial. The study, which was conducted in patients without diabetes, associated one year of metformin with a risk reduction relative to placebo of greater than 30%.
“Low-dose metformin was associated with a statistically significant reduction in the incidence of