The American College of Gastroenterology updated its 2017 guideline for treating Helicobacter pylori (Am J Gastroenterol 2024;119[9]:1730 10.14309/ajg.0000000000002968).
Despite a decreasing prevalence, up to 40% of people in the United States have H. pylori; many of the infections are asymptomatic.
In the new guideline, the No. 1 recommendation for treatment-naive patients is bismuth quadruple therapy. That treatment typically includes a proton pump inhibitor (PPI), tetracycline, bismuth