APRIL 3, 2019

Antibiotics and PPIs Linked to Increased C. diff Risk in Children

Prior antibiotic exposure and use of proton pump inhibitors may increase the risk for hospitalized children to contract Clostridioides difficile infections (Infect Control Hosp Epidemiol 2019 Mar 7. [Epub ahead of print]).

The incidence and health care burden of C. difficile infection (CDI) in hospitalized children has increased in the past two decades, mostly attributed to the emergence of a new hypervirulent strain of the bacteria. Although the risk factors are well understood in adult