Crypt dysplasia in patients with Barrett’s esophagus is associated with a high rate of histologic progression, according to a retrospective study in which patients were evaluated with a brush-based, computer-assisted sampling technique.
The study addressed a controversy that has been brewing for more than a decade. In the follow-up, the rate at which people with crypt dysplasia progressed to low-grade dysplasia (LGD) or worse was roughly 10% per year, according to Nicholas Shaheen, MD, the