SEPTEMBER 25, 2020

Newfound Mechanisms of Intestinal Fibrosis Could Lead to Prevention Strategies

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Florian Rieder, MD Cleveland Clinic

Intestinal fibrosis is a grim inevitability for many people with inflammatory bowel disease, especially Crohn’s disease. Approximately 60% of Crohn’s patients experience this complication, often requiring surgery to relieve strictures.

The traditional view of intestinal fibrosis is that it arises from the response of the gut tissues to persistent inflammation. But in recent years, researchers have begun to suspect that mechanisms besides