AUGUST 11, 2017

Combo Thiopurine/Anti-TNF Treatment Boosts Lymphoma Risk

People with inflammatory bowel disease who receive combination treatment with thiopurines and anti–tumor necrosis factor (TNF) agents have a nearly fivefold increased risk for lymphoma compared with those who receive neither class of medication, researchers have found.

According to a French study of more than 173,000 patients with IBD, the risk for lymphoma is more than twice as high with combination treatment with thiopurines and anti-TNF agents as it is with use of drugs from either