When it comes to treatment of refractory proctitis in people with inflammatory bowel disease, necessity gives birth to innovation.
With few effective options, researchers in the United Kingdom and Australia acted on a small body of evidence indicating topical tacrolimus may be effective and safe in these patients. However, a lack of approved tacrolimus suppositories or enemas meant they had to mix their own formulations. According to results reported at the 2019 annual meeting of the European