MAY 24, 2019

Excitement, Caution Greet Early Data For Etrasimod, Oral Agent for UC

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Michael Chiorean, MD

The selective, oral sphingosine 1-phosphate receptor modulator etrasimod was significantly more effective than placebo in inducing clinical and endoscopic response in a study of more than 150 patients with moderate to severe ulcerative colitis.

In the phase 2 OASIS trial, investigator Michael Chiorean, MD, the director of the IBD Center of Excellence at Virginia Mason’s Digestive Disease Institute in Seattle, and his colleagues randomly assigned 156 patients with