The addition of 5-aminosalicylic acid to corticosteroids does not improve outcomes in patients hospitalized with acute severe ulcerative colitis, according to findings from the first prospective randomized study evaluating this combination.
The study, which was presented at the 2022 Crohn’s & Colitis Congress and published in Gastroenterology (2022;28[suppl 1]:S14), sheds light on the management of a difficult-to-treat patient population, said lead researcher Shomron Ben-Horin, MD, the