Fecal microbiota transplantation appeared safe and beneficial in a small study of men with alcohol use disorder and cirrhosis.
The phase 1, randomized, double-blind controlled trial showed that FMT was associated with short-term reductions in alcohol craving and drinking, longer term reductions in alcohol-related events and positive changes in the microbiome, compared with placebo.
The significant findings were surprising, especially given the early phase and small sample size, said study author