San Diego—A slurry of budesonide is not better than inhaled fluticasone for controlling eosinophilic esophagitis, despite having a plausibly superior mechanism of action, a head-to-head study has found.
The hypothesis that the budesonide slurry would win over fluticasone in a direct comparison was based on the potential for its better drug contact in the esophagus at the site of inflammation. A previous meta-analysis of studies of the two approaches had supported greater efficacy for the