San Diego—One of the most comprehensive studies to date on the potential harms of proton pump inhibitors for gastric reflux has found no link between the drugs and a host of potential adverse events, ranging from fractures to dementia.
Previous analyses tended to be association studies with the disclaimer that prospective, randomized data are needed to confirm their findings. The new trial, with more than 17,000 randomized patients, provides that evidence.
With more than 53,000 years of