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| This section contains brief synopses of important articles recently published in peer-reviewed journals. |
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Industry-Sponsored Fospropofol Studies Retracted From Three Peer-Reviewed Journals
ISSUE: AUGUST, 2010 In another blow to industry-sponsored research—already under scrutiny for ghostwriting of journal papers—six studies published in three journals that assessed properties of fospropofol disodium (Aquavan, MGI Pharma Inc.; Lusedra, Eisai Inc.) have been retracted.
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Updated Guidelines for Publication of Clinical Trial Results Address Industry-Funded Writing Assistance
ISSUE: AUGUST, 2010 An established set of guidelines for reporting research results in journal articles has added a new item to its recommendations: In addition to funding, authors must clearly divulge any other source of support from a medical company, including writing assistance.
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Lancet Retracts Influential Paper After Undisclosed Conflicts Revealed
ISSUE: AUGUST, 2010 After more than a decade of criticism for publishing a scientifically weak study with far-reaching public health implications, The Lancet made a rare public retraction of a paper that suggested the measles, mumps and rubella vaccine was associated with the onset of autism.
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Editors Aim To Reveal Conflicts With New Disclosure Form
ISSUE: AUGUST, 2010 In an effort to promote transparency in medical writing, the International Committee of Medical Journal Editors has developed a new conflict-of-interest form for authors whose research is published in medical journals.
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Propofol Safe for Advanced Endoscopic Procedures, But Level of Sedation May Be Deeper Than Intended
Requires “Trained Professionals” Solely Responsible for Administering, Monitoring Sedation
ISSUE: JUNE, 2010 Propofol can be used safely in patients undergoing advanced endoscopic procedures—including endoscopic retrograde cholangiopancreatography, endoscopic ultrasound and small-bowel enteroscopy—when directed by certified registered nurse anesthetists, according to a prospective analysis of nearly 800 patients. However, 87.2% of patients in the study showed no response to endoscopic intubation—a sign the authors called a crude surrogate marker for measuring the depth of sedation.
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City-Dwelling Minorities With Hepatitis Show Lower Treatment Response Rates Than Patients Who Participate in Clinical Trials
ISSUE: MAY, 2010 Ethnic minorities, specifically those living in urban areas, have significantly lower response rates to the standard hepatitis C therapy of pegylated interferon and ribavirin than those reported in clinical trials, according to a new study.
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Recent Report of Hepatitis Outbreak Associated With Endoscopy Reminds Gastroenterologists To Be Vigilant About Infection Control
ISSUE: MAY, 2010 An article published in the March issue of Gastroenterology outlines the case of a single anesthesiologist who was responsible for 12 cases of hepatitis B and C arising from incorrect injection practices involving the re-use of syringes and single-dose propofol vials in patients undergoing endoscopy.
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Hepatitis C Infection Increases Risk for Kidney Cancer
ISSUE: MAY, 2010 Individuals infected with hepatitis C virus have more than twice the risk for renal cell carcinoma compared with HCV-negative individuals, according to researchers at Henry Ford Hospital in Detroit.
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